ACTIVELLA®—Prescription hormone therapy with an estrogen just like your own. Now you can replace what your body is missing with what you want in a hormone therapy.
ACTIVELLA® 0.5 mg/0.1 mg Tolerability and safety
ACTIVELLA® 0.5 mg/0.1 mg is FDA approved as safe and effective.1
The overall tolerability of ACTIVELLA® 0.5 mg/0.1 mg is comparable with placebo.8,9 6% of women taking ACTIVELLA® 0.5 mg/0.1 mg discontinued treatment due to side effects, versus 8% of those in the placebo group.8
The following breast disorders were reported in clinical trials at a frequency of 1% each.9
- Breast discomfort
- Breast pain
- Breast tenderness
The following treatment-emergent adverse events were reported at a frequency of ≥5%:1
- Back pain
- Nausea
- Headache
- Diarrhea
- Pain in extremity
- Nasopharyngitis
- Vaginal hemorrhage
- Endometrial thickening
- 1. ACTIVELLA® [package insert]. Princeton, NJ: Novo Nordisk Inc; 2007.
- 8. Panay N, Ylikorkala O, Archer DF, Gut R, Lang E. Ultra-low-dose estradiol and norethisterone acetate: effective menopausal symptom relief. Climacteric. 2007;10:120-131.
- 9. Data on file. CTR. Novo Nordisk Inc, Princeton, NJ. Trial ID: ALD-1537.
